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Because childhood should be simple ...

Alice Basinger, MD
Cook Children's Physician Network

Alice Basinger
Specialties:Metabolic Genetics
Education:Wake Forest University School of Medicine
Residency:University of North Carolina (Pediatrics & Clinical Genetics)
Fellowship:University of North Carolina (Clinical Biochemical Genetics)
Board Certified:Pediatrics


1300 W. Lancaster Ave.
Fort Worth, TX 76102
(682) 885-2170
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1002 S. Abe St., Ste. B
San Angelo, TX 76903
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PubMed ID19501198
Chan, S. S., Naviaux, R. K., BASINGER, A. A., Casas, K. A., & Copeland, W. C. (2009). De novo mutation in POLG leads to haplotype insufficiency and Alpers syndrome. Mitochondrion, (in press).
PubMed ID18546365
Wong, L.J.; Naviaux, R.K.; Brunetti-Pierri, N.; Zhang, Q.; Schmitt, E.S.; Truong, C.; Milone, M.; Cohen, B.H.; Wical, B. Ganesh, J.; BASINGER,A.A.; Burton, B.K.; Swoboda, K.; Gilbert, D.L.; Vanderver, A.; Saneto, R.P.; Maranda, B.; Arnold, G.; Abdenur, J.E.; Waters, P.J.; Copeland, W.C. (2008). Molecular and clinical genetics of mitochondrial diseases due to POLG mutations. Human Mutation, 29(9), e150-e172.
PubMed ID17506107
Kranz, C., BASINGER, A. A., Gucsavas-Calikoglu, M., Sun, L., Powell, C. M., Henderson, F. W. et al. (2007). Expanding spectrum of congenital disorder of glycosylation Ig (CDG-Ig): sibs with a unique skeletal dysplasia, hypogammaglobulinemia, cardiomyopathy, genital malformations, and early lethality. American journal of medical genetics.Part A, 143(12), 1371-1378.
PubMed ID16466958
BASINGER, A. A., Booker, J. K., Frazier, D. M., Koeberl, D. D., Sullivan, J. A., & Muenzer, J. (2006). Glutaric acidemia type 1 in patients of Lumbee heritage from North Carolina. Molecular genetics and metabolism, 88(1), 90-92.
Glutaric acidemia type I (GA-I) is an autosomal recessive disorder of the catabolism of lysine, hydroxylysine, and tryptophan caused by deficiency of glutaryl-CoA dehydrogenase (GCD). Among our patients with GA-I, we noted a prevalence of Lumbee individuals. The Lumbee are a close-knit Native American tribe of eastern North Carolina. Five Lumbee individuals with GA-I had homozygous 1240G>A mutations in GCD. This is a rare, known mutation that was likely introduced by a Lumbee founder.
Willis, M. S., BASINGER, A. A., Fan, S., Pendyal, J., Muenzer, J., & Hammett-Stabler, C. (2006). Hepatosplenomegaly in an 8-month-old child. Laboratory Medicine, 37(11), 1-6.
BASINGER, A. A., Frazier, D. M., Booker, J. K., & Muenzer, J. (March, 2005).Glutaric academia type 1 in patients of Lumbee heritage from North Carolina. Society for Inherited Metabolic Disorders Annual Meeting. Pacific Grove, CA.

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