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I joined the Neuroscience Program of Cook Children's in 2009 as a pediatric epileptologist, and now serve as the Medical Director of the Epilepsy Monitoring Unit and Tuberous Sclerosis Complex clinic. My clinical and research interests focus on the treatment of childhood onset epilepsy, specifically those patients with uncontrolled epilepsy or those for which the cause has not been determined. I have an intense interest in the use of surgical therapies to treat and cure epilepsy. The majority of my research has investigated the use of multimodal imaging techniques to localize seizure onset, as well as the description of patient and disease characteristics that predict favorable outcomes from surgical therapies. The pool of candidates which may benefit from surgical therapy continues to expand and I came to Cook Children's specifically because the staff of the Epilepsy Monitoring Unit and Comprehensive Epilepsy Program were dedicated to improving the care of children with epilepsy through cutting-edge techniques, research, and concern for their patients' well being.
In addition to my interest in surgical therapies, I care for a number of patients with epilepsy secondary to genetic disease. As our understanding of epilepsy has progressed and the sophistication of genetic testing has evolved, many new gene mutations have been discovered which lead to epilepsy. These syndromes often have certain characteristics for which treatment choices may be altered and outcome changed based on understanding the genetic mutation present. Many patients may have suffered years with uncontrolled epilepsy of unknown cause, but upon reevaluation a diagnosis may be made. With these patients in mind, I created the Genetic Epilepsy Clinic at Cook Children's, along with my partners in genetics, to improve the diagnosis, understanding, and treatment of children with these rare conditions.
Outside of my clinical and research interests, I serve on a number of local, national, and international committees dedicated to improving the care of childhood onset epilepsy. My free time is often spent with my wife and two daughters- usually at one of their dance competitions. I enjoy music of all types as well as collecting art, especially pieces related to the blues and my childhood home of the Mississippi Delta region.
Brna P, Dooley JM, Esser JM, Perry MS, Gordon KE. Are YouTube seizures misleading? Neurologists don’t always agree. Epilepsy and Behavior 2013, 29(2):305-7.
Perry MS, Duchowny MS. Surgical versus medical treatment for refractory epilepsy: outcomes beyond seizure control. Epilepsia 2013, 54(12): 2060-70.
Little W, Perry MS, Simon HK. Headache in the Pediatric Patient. In Harwood-Nuss’ The Clinical Practice of Emergency Medicine, 6th Ed. Philadelphia, PA: Lippincott Williams & Wilkins, 2013
Perry MS, Duchowny MS. Evaluation of intractable epilepsy. In Principles and Practice of Pediatric Neurosurgery, 3rd Ed. (eds Albright L, Pollack I, Adelson D) Thieme Medical Publishers.
Sankar S, Chung S, Perry MS, Kuzniecky R, Sinha S. Clinical considerations in transitioning patients with epilepsy from clonazepam to clobazam: acase series. J Med Case Rep, 2014, Dec 16;8:429.
Perry MS and Patel AD. American Board of Psychiatry and Neurology Certification in Epilepsy: Just what the doctor ordered, another board examination. Pediatric Neurology 2014, 51(5):598-599.
Elias H, Perry MS. “Tuberous Sclerosis” In Dieckmann RA, Pitt WR, Schafermeyer RW, Young K, Fox S (editors-in-chief): "PEMSoft: The Pediatric Emergency Medicine Software", Version 9.0. EBSCO Publishing, Massachusetts, 2015.
Elias H, Perry MS. “Infantile spasms” In Dieckmann RA, Pitt WR, Schafermeyer RW, Young K, Fox S (editors-in-chief): "PEMSoft: The Pediatric Emergency Medicine Software", Version 9.0. EBSCO Publishing, Massachusetts, 2015.
Elias H, Perry MS. “Sturge Weber Syndrome” In Dieckmann RA, Pitt WR, Schafermeyer RW, Young K, Fox S (editors-in-chief): "PEMSoft: The Pediatric Emergency Medicine Software", Version 9.0. EBSCO Publishing, Massachusetts, 2015.Perry MS. (2015) “Tuberous Sclerosis Complex” Epilepsy.com
Perry MS. Has progress been made in progressive myoclonic epilepsy (EPM1)?. Epilepsy Curr 2015, 15(5):253-254.Fournier-Goodnight A, Gabriel M, Perry MS. Preliminary neurocognitive outcomes in Jeavons Syndrome. Epilepsy Behav 2015, 52(Pt A):260-263.
Hodges SL, Gabriel MT, Perry MS. Neuropsychological Findings Associated with Panayiotopoulos Syndrome. Epilepsy Behav 2016;54:158-162.
Daniel C, Perry MS. Ictal Coprolalia: A Case Report and Review of Ictal Speech as a Localizing Feature in Epilepsy. Ped Neuro 2016 (in press)
Perry MS. Genetic testing in epileptic encephalopathy: Rosetta stone or just an expensive rock? Epilepsy Curr 2016, 16(1):12-13.
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