Meet Dr. Santhisree Kopalli

As a pediatrician, I'm truly happiest when I see the positive changes I can make in a child's life and watch them grow into happy, healthy individuals. Whether I'm helping a parent through a tough time, guiding a child through their milestones, or supporting teenagers with their complex emotions, every part of this work feels incredibly rewarding. I love building strong connections with families, providing caring support, and knowing that I'm making a difference in a child's well-being.

I knew from an early age that I wanted to become a doctor. I used to bandage up my stuffed animals, and my love for science has always been most fulfilling when it's applied to real people and real situations. By the time I was in my third year of medical school, I had fallen in love with pediatrics. I found myself constantly thinking about my young patients, eagerly anticipating the moments I could return to care for them.

Being a parent to two wonderful kids has deepened my understanding of the concerns that families face. It helps me connect more meaningfully with families and offer the most compassionate care. I truly enjoy talking with children and teenagers, taking the time to explain things in ways they can understand, and addressing their individual worries. Building these relationships helps me encourage healthy habits and support children and teens in reaching their goals. Seeing them grow into happy, healthy adults is incredibly rewarding.

I began my medical career in India, completing my education at the esteemed Guntur Medical College, before pursuing Pediatric residency at Texas Tech University in El Paso. Prior to joining Cook Children's in Aubrey, I gained extensive experience at Renner Pediatrics in Richardson and Craig Ranch Pediatrics in McKinney, Texas. I am married to Rajasekhar, a software architect, and we are blessed with two wonderful children, Sidharth and Saila. Outside of my professional life, I derive great joy from traveling, cooking, and spending cherished moments with my family.

While I'm equipped to handle a wide range of medical issues, I have a special interest in allergies, asthma, and skin conditions. I'm passionate about working with kids and teens of all ages, striving every day to provide top-notch care that addresses both their physical and emotional health. I believe in empowering parents with the knowledge they need to make the best decisions for their children and love educating families to help them take charge of their health.

Services

  • Acute illnesses
  • ADHD management
  • Chronic condition management
  • Developmental problems
  • Disease prevention
  • Flu shots
  • Hearing screens
  • Injury treatment
  • Newborn classes
  • Obesity and weight management
  • Vision screens
  • Patient and parent education
  • School and sports physicals
  • Vaccines and immunizations
  • Well checks

Reviews

Average rating:

4.8
Questions were addressed
4.8
4.8 (40)
Provider explained things clearly
4.8
4.8 (40)
Likelihood of recommending this provider
4.8
4.8 (40)
Trust/confidence in physicians
4.8
4.8 (38)

What our families say

  • November 14, 2025

    Dr.Kopalli is very nice towards kids and her explanation is very nice

  • November 09, 2025

    All Good

  • September 19, 2025

    Everyone was very kind caring and helpful

  • September 11, 2025

    Dr Santhisree was awesome. She listened to all of our questions as a first time parent and answered them patiently. She is very knowledgeable and cares about kids.

  • August 22, 2025

    Dr. Kopalli is one of the best we've ever been to

  • August 14, 2025

    Good

  • August 14, 2025

    Good

  • August 14, 2025

    Good, no bad experience at all.

  • August 14, 2025

    1. Staffing nurse is very humble and polite.2. DR Santhisree has examined my child with almost care and given valuable feedback and suggestions.

  • August 05, 2025

    Good

  • May 29, 2025

    We love our visits every time! Reccomend this place 10/10

  • May 11, 2025

    Everyone was very friendly and helpful

  • May 03, 2025

    Thank you, everyone. I have no complaints

  • March 14, 2025

    Kopalli made my children so comfortable, that my 11 year old doesn't want to see any other doctor! Our 4year old twins had a ball like it was a playground. There vaccinations went extremely well... No crying... And very social with the staff. They made the experience fun for them!

  • February 27, 2025

    It was very good experience. I used visiting there for my younger. I got appointments within an hour and treat my kid in next one hour.

  • December 18, 2024

    Excellent

  • December 18, 2024

    The staff and Doctor were amazing. I just moved to this provider from a 5 year relationship with my previous provider and I am looking forward to this new doctor

  • December 18, 2024

    This was the easiest, quickest visit I have ever had at any doctors office. The care we received was wonderful and my child was made very comfortable. Thank you so much!

  • December 15, 2024

    Doctor Was attentive to concerns, helpful and informative

  • December 15, 2024

    Front staff were very nice and helpful when setting up portal

Dr. Kopalli with baby.
Dr. Kopalli
Dr. Kopalli with patient

Education

  • Medical school:
  • Government General Hospital, Andhra Pradesh, India
  • Residency:
  • Texas Tech University of Health Sciences Center, EL Paso, TX
  • Board certifications:
  • American Board of Pediatrics

Affiliations

  • Cook Children's Physician Network
  • American Academy of Pediatrics Texas medical board

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