Neuroscience Published Research
Selected Publications
Matarrese, M.A. G., Loppini, A., Fabbri, L., Tamilia, E., Perry, M. S., Madsen, J. R., Bolton, J., Stone, S. S. D., Pearl, P. L., Filippi, S., Papadelis, C. (2023). Spike propagation mapping reveals effective connectivity and predicts surgical outcome in epilepsy. Brain: a journal of neurology, awad118. Advance online publication. https://doi.org/10.1093/brain/awad118.
Corona, L., Tamilia, E., Perry, M. S., Madsen, J. R., Bolton, J., Stone, S. S., Stufflebeam, S. M., Pearl, P. L., & Papadelis, C. (2023). Non-invasive mapping of epileptogenic networks predicts surgical outcome. Brain : a journal of neurology, 146(5), 1961-1931.https://doi.org/10.1093/brain/awac477.
Perry, M. S., Shandley, S., Perelman, M., Singh, R. K., Wong-Kisiel, L., Sullivan, J., Gonzalez-Giraldo, E., Romanowski, E. F., McNamara, N. A., Marashly, A., Ostendorf, A. P., Alexander, A., Eschbach, K., Bolton, J., Wolf, S., McGoldrick, P., Depositario-Cabacar, D. F., Ciliberto, M. A., Gedela, S., Sannagowdara, K., … Coryell, J. (2022). Surgical evaluation in children <3 years of age with drug- resistant epilepsy: Patient characteristics, diagnostic utilization, and potential for treatment delays. Epilepsia, 63(1), 96–107. https://doi.org/10.1111/epi.17124.
Tamilia, E., Matarrese, M., Ntolkeras, G., Grant, P. E., Madsen, J. R., Stufflebeam, S. M., Pearl, P. L., & Papadelis, C. (2021). Noninvasive Mapping of Ripple Onset Predicts Outcome in Epilepsy Surgery. Annals of neurology, 89(5), 911–925. https://doi.org/10.1002/ana.26066.
Tamilia, E., Dirodi, M., Alhilani, M., Grant, P. E., Madsen, J. R., Stufflebeam, S. M., Pearl, P. L., & Papadelis, C. (2020). Scalp ripples as prognostic biomarkers of epileptogenicity in pediatric surgery. Annals of clinical and translational neurology, 7(3), 329–342. https://doi.org/10.1002/acn3.50994.
2023
Publications in Scientific Journals:
- Chikara, R. K., Jahromi, S., Tamilia, E., Madsen, J. R., Stufflebeam, S. M., Pearl, P. L., & Papadelis, C. (2023). Electromagnetic source imaging predicts surgical outcome in children with focal cortical dysplasia. Clinical neurophysiology: official journal of the International Federation of Clinical Neurophysiology. 153, 88-101. https://doi.org/10.1016/j.clinph.2023.06.015.
- Rijal, S., Corona, L., Perry, M. S., Tamilia, E., Madsen, J. R., Stone, S. S. D., Bolton, J., Pearl, P. L., & Papadelis, C. (2023). Functional connectivity discriminates epileptogenic states and predicts surgical outcome in children with drug resistant epilepsy. Scientific reports, 13(1), 9622. https://doi.org/10.1038/s41598-023-36551-0.
- Matarrese, M. G., Loppini, A., Fabbri, L., Tamilia, E., Perry, M. S., Madsen, J. R., Bolton, J., Stone, S. S. D., Pearl, P. L., Filippi, S., Papadelis, C. (2023). Spike propagation mapping reveals effective connectivity and predicts surgical outcome in epilepsy. Brain: a journal of neurology, awad118. Advance online publication. https://doi.org/10.1093/brain/awad118.
- Corona, L., Tamilia, E., Perry, M. S., Madsen, J. R., Bolton, J., Stone, S. S., Stufflebeam, S. M., Pearl, P. L., & Papadelis, C. (2023). Non-invasive mapping of epileptogenic networks predicts surgical outcome. Brain : a journal of neurology, 146(5), 1961-1931.https://doi.org/10.1093/brain/awac477.
- Beatty, C. W., Ahrens, S. M., Arredondo, K. H., Bagić, A. I., Bai, S., Chapman, K. E., Ciliberto, M. A., Clarke, D. F., Eisner, M., Fountain, N. B., Gavvala, J. R., Perry, M. S., Rossi, K. C., Wong-Kisiel, L. C., Herman, S. T., Ostendorf, A. P., & NAEC Center Director Study Group. (2023). Associations between testing and treatment pathways in lesional temporal or extratemporal testing and treatment pathways in epilepsy surgery: A census survey of 342 NAEC center directors. https://doi.org/10.1111/epi.17512.
- Chericon,i A*., Ricci, L*., Ntolkeras, G., Billardello, R., Stone, SSD., Madsen, J.R., Papadelis, C., Grant, P.E., Pearl, P.L., Taffoni, F., Rotenberg, A., Tamilia, E. (2023). Sleep spindle generation before and after epilepsy surgery: A source imaging study in Children with Drug Resistant Epilepsy. Brain Topography 2023; In Press.
- Papadelis, C., Ntolkeras, G., DiBacco, M.L., Afacan, O., Warfield, S., Shi, X., Roullet, J-B., Gibson, K.M., SSADHD Study Group, Pearl, P.L. (2023). Reduced evoked cortical beta and gamma activity and neuronal synchronization in SSADH Deficiency, a Disorder of GABA Metabolism. Brain Communications 2023; In Press.
- Manwar R, Kratkiewicz K, Mahmoodkalayeh S, Hariri A, Papadelis C, Hansen A, Pillers DM, Gelovani J, Avanaki K. Photoacoustics 2023; 100538.
- Tokatly LI, Hanson E, Bertoldi M, García-Cazorla À, Tsuboyama M, MacMullin P, Rotenberg A, Roullet JB, Pearl PL; SSADH Deficiency Investigators Consortium*. Autism spectrum disorder and GABA levels in children with succinic semialdehyde dehydrogenase deficiency. Dev Med Child Neurol. 2023 May 28. doi: 10.1111/dmcn.15659. Papadelis C is listed as member of the SSADH Deficiency Investigators Consortium
2022
Publications in Scientific Journals:
- Yossofzai, O., Stone, S., Madsen, J., Moineddin, R., Wang, S., Ragheb, J., Mohamed, I., Bollo, R., Clarke, D., Perry, M. S., Weil, A. G., Raskin, J., Pindrik, J., Ahmed, R., Lam, S., Fallah, A., Maniquis, C., Andrade, A., Ibrahim, G. M., Drake, J., … Widjaja, E. (2022). Seizure Outcome of Pediatric MR-guided Laser Interstitial Thermal Therapy versus Open Surgery: A Matched Non-Inferiority Cohort Study. Epilepsia, 10.1111/epi.17451. Advance online publication. https://doi.org/10.1111/epi.17451.
- Ahrens, S. M., Arredondo, K. H., Bagic, A. I., Bai, S., Chapman, K. E., Ciliberto, M. A., Clarke, D. F., Eisner, M., Fountain, N. B., Gavvala, J. R., Perry, M. S., Rossi, K. C., Wong-Kisiel, L. C., Herman, S. T., Ostendorf, A. P., & NAEC Center Director Study Group (2022). Epilepsy center characteristics and geographic region influence presurgical testing in the United States. Epilepsia, 1111/epi.17452. Advance online publication. https://doi.org/10.1111/epi.17452.
- McKnight, D., Morales, A., Hatchell, K. E., Bristow, S. L., Bonkowsky, J. L., Perry, M. S., Berg, A. T., Borlot, F., Esplin, E. D., Moretz, C., Angione, K., Ríos-Pohl, L., Nussbaum, R. L., Aradhya, S., & the ELEVIATE Consortium. (2022). Genetic testing to inform epilepsy treatment management from an international study of clinical practice. JAMA Neurology. https://doi.org/10.1001/jamaneurol.2022.3651.
- Obaid, S., Chen, J. S., Ibrahim, G. M., Bouthillier, A., Dimentberg, E., Surbeck, W., Guadagno, E., Brunette-Clément, T., Shlobin, N. A., Shulkin, A., Hale, A. T., Tomycz, L. D., Von Lehe, M., Perry, M. S., Chassoux, F., Bouilleret, V., Taussig, D., Fohlen, M., Dorfmiller, G., Hagiwara, K., … Weil, A. G. (2022). Predictors of outcomes after surgery for medically intractable insular epilepsy: A systematic review and individual participant data meta-analysis. Epilepsia open, 1002/epi4.12663. Advance online publication. https://doi.org/10.1002/epi.4.12663.
- Arredondo, K. H., Ahrens, S. M., Bagic, A. I., Bai, S., Chapman, K. E., Ciliberto, M. A., Clarke, D. F., Eisner, M., Fountain, N. B., Gavvala, J. R., Perry, M. S., Rossi, K. C., Wong-Kisiel, L. C., Herman, S. T., & Ostendorf, A. P. (2022). Association Between Characteristics of National Association of Epilepsy Centers and Reported Utilization of Specific Surgical Techniques. Neurology, 10.1212/WNL.0000000000201526. Advance online publication. https://doi.org/10.1212/WNL.0000000000201526.
- Zhou, Y., You, J., Kumar, U., Weiss, S. A., Bragin, A., Engel, J., Jr, Papadelis, C., & Li, L. (2022). An approach for reliably identifying high-frequency oscillations and reducing false positive detections. Epilepsia open, 1002/epi4.12647. Advance online publication. https://doi.org/10.1002/epi4.12647.
- Nascimento, F. A., Jing, J., Strowd, R., Sheikh, I. S., Weber, D., Gavvala, J. R., Maheshwari, A., Tanner, A., Ng, M., Vinayan, K. P., Sinha, S. R., Yacubian, E. M., Rao, V. R., Perry, M. S., Fountain, N. B., Karakis, I., Wirrell, E., Yuan, F., Friedman, D., Tankisi, H., … Beniczky, S. (2022). Competency-based EEG education: a list of "must-know" EEG findings for adult and child neurology residents. Competency-based EEG education: a list of “must-know” EEG findings for adult and child neurology residents. Epileptic disorders : international epilepsy journal with videotape, 24(5), 1–4. https://doi.org/10.1684/epd.2022.1476.
- Papadelis, C., Ricci, L., Matarrese, M., Peters, J. M., Tamilia, E., Madsen, J., & Pearl, P. L. (2022). Reply to "Added value of high-resolution electrical source imaging of ictal activity in children with structural focal epilepsy". Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 140, 254–255. https://doi.org/10.1016/j.clinph.2022.06.001
- Trombello, J. M., Cooper, C. M., Fatt, C. C., Grannemann, B. D., Carmody, T. J., Jha, M. K., Mayes, T. L., Greer, T. L., Yezhuvath, U., Aslan, S., Pizzagalli, D. A., Weissman, M. M., Webb, C. A., Dillon, D. G., McGrath, P. J., Fava, M., Parsey, R. V., McInnis, M. G., Etkin, A., & Trivedi, M. H. (2022). Neural substrates of emotional conflict with anxiety in major depressive disorder: Findings from the Establishing Moderators and biosignatures of Antidepressant Response in Clinical Care (EMBARC) randomized controlled trial. Journal of psychiatric research, 149, 243– https://doi.org/10.1016/j.jpsychires.2022.03.015.
- Brunklaus, A., Brünger, T., Feng, T., Fons, C., Lehikoinen, A., Panagiotakaki, E., Vintan, M. A., Symonds, J., Andrew, J., Arzimanoglou, A., Delima, S., Gallois, J., Hanrahan, D., Lesca, G., MacLeod, S., Marjanovic, D., McTague, A., Nuñez-Enamorado, N., Perez-Palma, E., Scott Perry, M., … Cestèle, S. (2022). The gain of function SCN1A disorder spectrum: novel epilepsy phenotypes and therapeutic implications. Brain : a journal of neurology, awac210. Advance online publication. https://doi.org/10.1093/brain/awac210.
- Dimakopoulos, V., Gotman, J., Stacey, W., von Ellenrieder, N., Jacobs, J., Papadelis, C., Cimbalnik, J., Worrell, G., Sperling, M. R., Zijlmans, M., Imbach, L., Frauscher, B., & Sarnthein, J. (2022). Protocol for multicentre comparison of interictal high-frequency oscillations as a predictor of seizure freedom. Brain communications, 4(3), fcac151. https://doi.org/10.1093/braincomms/fcac151.
- Niu, H., Ming, D., Papadelis, C., & Alexandrakis, G. (2022). Editorial: The Brain Under Fatigue, Frontiers in Neuroscience, 16:945527. https://doi.org/10.3389/fnins.2022.945527,
- Malik, S. (2022). Magnetoencephalography: at the forefront of optimizing epilepsy surgery. Future Neurology, 1748-6971, https://10.2217/fnl-2022-0006.
- Cromwell, H. C., & Papadelis, C. (2022). Mapping the brain basis of feelings, emotions and much more: A special issue focused on ‘The Human Affectome’. Neuroscience and biobehavioral reviews, 137, Advance online publication. https://doi.org/10.1016/j.neubiorev.2022.104672.
- Billardello, R., Ntolkeras, G., Chericoni, A., Madsen, J. R., Papadelis, C., Pearl, P. L., Grant, E., Taffoni, F., & Tamilia, E. (2022). Novel User-Friendly Application for MRI Segmentation of Brain Resection following Epilepsy Surgery. Diagonostics (Basel, Switzerland), 12(4), 1017. https://doi.org/10.3390/diagnostics12041017.
- Ricci, L., Matarrese, M., Peters, J. M., Tamilia, E., Madsen, J. R., Pearl, P. L., & Papadelis, C. (2022). Virtual Implantation using Conventional Scalp EEG Delineates Seizure Onset and Predicts Surgical Outcome in Children with Epilepsy, Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 139, 49-57. Advance online publication. https://doi.org/10.1016/j.clinph.2022.04.009.
- Hood, V., Berg, A. T., Knupp, K. G., Koh, S., Laux, L., Meskis, M. A., Zulfiqar-Ali, Q., Perry, M. S., Scheffer, I. E., Sullivan, J., Wirrell, E., & Andrade, D. M. (2022). COVID-19 vaccine in patients with Dravet syndrome: Observations and real-world experiences. Epilepsia, 63(7), 1778–1786. https://doi.org/10.1111/epi.17250.
- Samanta, D., Ostendorf, A. P., Singh, R., Gedela, S., Elumalai, V., Leigh, M. L., Perry, M. S., Bartolini, L., & Curran G. M. (2022). Physicians’ Perspectives on Presurgical Discussion and Shared Decision-Making in Pediatric Epilepsy Surgery. Journal of Child Neurology, (1-10). https://doi.org/10-1177/08830738221089472.
- Papadelis, C., Conrad, S. E., Song, Y., Shandley, S., Hansen, D., Bosemani, M., Malik, S., Keator, C., & Perry, M. S. (2022). Case Report: Laser Ablation Guided by State of the Art Source Imaging Ends an Adolescent’s 16-Year Quest for Seizure Freedom. Frontiers in Human Neuroscience, 16:https://doi.org/10.3389/frhum.2022.826139.
- Knupp, K. G., Coryell, J., Singh, R. K., Gaillard, W. D., Shellhaas, R. A., Koh, S., Mitchell, W. G., Harini, , Millichap, J. J., May, A., Dlugos, D., Nickels, K., Mytinger, J. R., Keator, C., Yozawitz, E., Singhal, N., Lockrow, J., Thomas, J. F., & Juarez-Colunga, E. (2022). Comparison of Cosyntropin, Vigabatrin, and Combination Therapy in New-Onset Infantile Spasms in a Prospective Randomized Trial. Journal of child neurology, 8830738211073400. Advance online publication. https://doi.org/10.1177/08830738211073400.
- Jones, M., Harris, W. B., Perry, M. S., Behrmann, M., Christodoulou, J., Fallah, A., Kolb, B., Musiek, F., Paul, L. K., Puka, K., Salorio, C., Sankar, R., Smith, M. L., Moosa, A. M. N., Walshaw, P., Weiner, H. L., Woo, R., Zeitler, P., & Abel, T. J. (2022). Knowledge gaps for functional outcomes after multilobar resective and disconnective pediatric epilepsy surgery: Conference proceedings of the patient-centered stakeholder meeting 2019. Epileptic disorders: international epilepsy journal with videotape,, 24(1), 1-17. https://doi.org/10.1684/epd.2021.1373.
- Ntolkeras, G., Tamilia, E., AlHilani, M., Bolton, J., Ellen Grant, P., Prabhu, S. P., Madsen, J. R., Stufflebeam, S. M., Pearl, P. L., & Papadelis, C. (2022). Presurgical accuracy of dipole clustering in MRI-negative pediatric patients with epilepsy: Validation against intracranial EEG and resection. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 141, 126–138. https://doi.org/10.1016/j.clinph.2021.01.036.
2021
Publications in Scientific Journals:
- Perry, M. S., Shandley, S., Perelman, M., Singh, R. K., Wong-Kisiel, L., Sullivan, J., Gonzalez-Giraldo, , Romanowski, E. F., McNamara, N. A., Marashly, A., Ostendorf, A. P., Alexander, A., Eschbach, K., Bolton, J., Wolf, S., McGoldrick, P., Depositario-Cabacar, D. F., Ciliberto, M. A., Gedela, S., Sannagowdara, K., … Coryell, J. (2022). Surgical evaluation in children <3 years of age with drug- resistant epilepsy: Patient characteristics, diagnostic utilization, and potential for treatment delays. Epilepsia, 63(1), 96–107. https://doi.org/10.1111/epi.17124.
- Nguyen, K. P., Fatt, C. C., Treacher, A., Mellema, C., Cooper, C., Jha, M. K., Kurian, B., Fava, M., McGrath, P. J., Weissman, M., Phillips, M. L., Trivedi, M. H., & Montillo, A. A. (2021). Patterns of Pretreatment Reward Task Brain Activation Predict Individual Antidepressant Response: Key Results from the EMBARC Randomized Clinical Trial, Biological psychiatry, S0006- 3223(21)01600-0. Advance online publication. https://doi/org/10.1016/j.biopsych.2021.09.011.
- Sullivan, J., Specchio, N., Devinsky, O., Auvin, S., Perry, M. S., Strzelczyk, A., Gil-Nagal, A., Dai, D., Galer, B. S., & Gammaitoni, A. R. (2021). Fenfluramine significantly reduces day-to-day seizure burden by increasing number of seizure-free days and time between seizures in patients with Dravet syndrome: A time-to-event analysis. Epilepsia, 1-9. https://doi.org/10.1111/epi.17106.
- Liu, S., Aldinger, K. A., Cheng, C. V., Kiyama, T., Dave, M., McNamara, H. K., Zhao, W., Caraffi, S. G., Ivanovski, I., Errichiello, E., Zweier, C., Zuffardi, O., Schneider, M., Papavasiliou, A. S., Perry, M. , Humberson, J., Cho, M. T., Weber, A., Swale, A., Badea, T. C., … Reinberg, D. (2021). NRF1 association with AUTS2-Polycomb mediates specific gene activation in the brain. Molecular cell, S1097- 2765(21)00754-1. Advance online publication. https://doi.org/10.1016/j.molcel.2021.09.020.
- Song, Y., Renoul, E., Acord, S., Johnson, Y. R., Marks, W.,Alexandrakis, G., & Papadelis, C. (2021). Aberrant somatosensory phase synchronization in children with hemiplegic cerebral Neuroscience letters, 762, 136169. https://doi.org/10.1016/j.neulet.2021.136169.
- Lepard, J. R., Kim, I., Arynchyna, A., Lew, S. M., Bollo, R. J., O'Neill, B. R., Perry, M. S., Donahue, D., Smyth, M. D., & Blount, J. (2021). Early implementation of stereoelectroencephalography in children: a multiinstitutional case series. Journal of neurosurgery. Pediatrics, 1–8. Advance online publication. https://doi.org/10.3171/2021.5.PEDS20923.
- Andrade, D. M., Berg, A. T., Hood, V., Knupp, K. G., Koh, S., Laux, L., Meskis, M. A., Miller, I., Perry, S., Scheffer, I. E., Sullivan, J., Villas, N., & Wirrell, E. (2021). Dravet syndrome: A quick transition guide for the adult neurologist. Epilepsy research, 177, 106743. https://doi.org/10.1016/j.eplepsyres.2021.106743.
- Samanta, D., Hoyt, M. L., & Perry, M. S. (2021). Parental experience and decision-making for epilepsy surgery: A systematic review of qualitative and quantitative studies. Epilepsy & behavior : E&B, 123, 108263. https://doi.org/10.1016/j.yebeh.2021.108263.
- Ntolkeras, G., Chericoni, A., Madsen, J., Grant, E., Pearl, P., Papadelis, C., & Tamilia, E. (2021). Non- invasive electrophysiological signatures of the epileptogenic zone in children with focal drug resistant epilepsy. In Annals of Neurology (Vol. 90, pp. S57-S59). 111 River St, Hoboken 07030- 5774, NJ USA: Wiley.
- El Atrache, R., Tamilia, E., Amengual-Gual, M., Mohammadpour Touserkani, F., Yang, Y., Wang, X., Ufongene, C., Sheehan, T., Cantley, S., Jackson, M., Zhang, B., Papadelis, C., Sarkis, R. A., & Loddenkemper, T. (2021). Association between semiologic, autonomic, and electrographic seizure characteristics in children with generalized tonic-clonic seizures. Epilepsy & behavior : E&B, 122, 108228. https://doi.org/10.1016/j.yebeh.2021.108228
- Gil-Nagel, A., Sullivan, J., Ceulemans, B., Wirrell, E., Devinsky, O., Nabbout, R., Knupp, K. G., Scott Perry, M., Polster, T., Davis, R., Lock, M., Cortes, R. M., Gammaiton, A. R., Farfel, G., Galer, B. S., & Agarwal, A. (2021). Treatment with fenfluramine in patients with Dravet syndrome has no long-term effects on weight and growth. Epilepsy & behavior : E&B, 122, 108212. https://doi.org/10.1016/j.yebeh.2021.108212.
- He, C., Chikara, R. K., Yeh, C. L., & Ko, L. W. (2021). Neural Dynamics of Target Detection via Wireless EEG in Embodied Cognition. Sensors (Basel, Switzerland), 21(15), 5213. https://doi.org/10.3390/s21155213.
- Papadelis, C., & Perry, M.S. (2021). Localizing the epileptogenic zone with novel biomarkers. Seminars in pediatric neurology, 39, https://dio.org/10.1016/j.spen.2021.100919.
- Iandolo, G., Chourasia, N., Ntolkeras, G., Madsen, J. R., Papadelis, C., Grant, E., Pearl, P. L., Taffoni, , & Tamilia, E. (2021). Changes in the Functional Brain Network of Children Undergoing Repeated Epilepsy Surgery: An EEG Source Connectivity Study. Diagnostics (Basel, Switzerland), 11(7), 1234. https://doi.org/10.3390/diagnostics11071234.
- Ricci, L., Tamilia, E., Alhilani, M., Alter, A., Scott Perry, Μ., Madsen, J. R., Peters, J. M., Pearl, P. L., & Papadelis, C. (2021). Source imaging of seizure onset predicts surgical outcome in pediatric Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 132(7), 1622–1635. https://doi.org/10.1016/j.clinph.2021.03.043.
- Samanta, D., Leigh Hoyt, M., & Scott Perry, M. (2021). Healthcare professionals' knowledge, attitude, and perception of epilepsy surgery: A systematic review. Epilepsy & behavior : E&B, 122, 108199. https://doi.org/10.1016/j.yebeh.2021.108199.
- Keator C. G. (2021). Epilepsy Surgery is a Viable Treatment for Lennox Gastaut Syndrome. Seminars in pediatric neurology, 38, 100894. https://doi.org/10.1016/j.spen.2021.100894.
- Patel, A. D., Mazurkiewicz-Bełdzińska, M., Chin, R. F., Gil-Nagel, A., Gunning, B., Halford, J. J., Mitchell, W., Scott Perry, M., Thiele, E. A., Weinstock, A., Dunayevich, E., Checketts, D., & Devinsky, O. (2021). Long-term safety and efficacy of add-on cannabidiol in patients with Lennox-Gastaut syndrome: Results of a long-term open-label extension trial. Epilepsia, 62(9), 2228–2239. https://doi.org/10.1111/epi.17000.
- Finkel, R. S., McDonald, C. M., Lee Sweeney, H., Finanger, E., Neil Knierbein, E., Wagner, K. R., Mathews, K. D., Marks, W., Statland, J., Nance, J., McMillan, H. J., McCullagh, G., Tian, C., Ryan, M., O'Rourke, D., Müller-Felber, W., Tulinius, M., Burnette, W. B., Nguyen, C. T., Vijayakumar, K., Johannsen, J., Phan, H. C., Eagle, M., MacDougall, J., Mancini, M., Donovan, J. M., (For the PolarisDMD Study Group) (2021). A Randomized, Double-Blind, Placebo-Controlled, Global Phase 3 Study of Edasalonexent in Pediatric Patients with Duchenne Muscular Dystrophy: Results of the PolarisDMD Trial. Journal of neuromuscular diseases, 8(5), 769–784. https://doi.org/10.3233/JND-210689.
- Koy, A., Kühn, A. A., Hubel, J., Schneider, G-H., van Riesen, A., K., Eckenweiler, M., Rensing- Zimmerman, C., Coenen, V. A.,…Marks, W. A.,…& STIM-CP investigators (2021). Quality of Life after Deep Brain Stimulation of Pediatric Patients With Dyskinetic Cerebral Palsy: A Prospective, Single-Arm, Multicenter Study With a Subsequent Randomized Double-Blind Crossover (STIM- CP). Movement disorders : official journal of the Movement Disorder Society, 1002/mds.28898. Advance online publication. https://doi.org/10.1002/mds.28898.
- Grinspan, Z. M., Knupp, K. G., Patel, A. D., Yozawitz, E. G., Wusthoff, C. J., Wirrell, E., Valencia, I., Singhal, N. S., Nordli, D. R., Mytinger, J. R., Mitchell, W., Keator, C. G., Loddenkemper, T., Hussain, S. A., Harini, C., Gaillard, W. D., Fernandez, I. S., Coryell, J., Chu, C. J., Berg, A. T., Shellhaas, R. A. (2021). Comparative Effectiveness of Initial Treatment for Infantile Spasms in a Contemporary US Cohort. Neurology, 97(12), e1217–e1228. Advance online publication. https://doi.org/10.1212/WNL.0000000000012511.
- Ntolkeras, G., Tamilia, E., AlHilani, M., Bolton, J., Ellen Grant, P., Prabhu, S. P., Madsen, J. R., Stufflebeam, S. M., Pearl, P. L., & Papadelis, C. (2021). Presurgical accuracy of dipole clustering in MRI-negative pediatric patients with epilepsy: Validation against intracranial EEG and Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, S1388-2457(21)00480-6. Advance online publication. https://doi.org/10.1016/j.clinph.2021.01.036.
- Johannesen, K. M., Liu, Y., Koko, M., Gjerulfsen, C. E., Sonnenberg, L., Schubert, J., Fenger, C. D., Eltokhi, , Rannap, M., Koch, N. A., Lauxmann, S., Krüger, J., Kegele, J., Canafoglia, L., Franceschetti, S., Mayer, T., Rebstock, J., Zacher, P., Ruf, S., Alber, M., Perry, M.S., … Møller, R. S. (2021). Genotype-phenotype correlations in SCN8A-related disorders reveal prognostic and therapeutic implications. Brain : a journal of neurology, awab321. Advance online publication. https://doi.org/10.1093/brain/awab321.
- Tamilia, E., Matarrese, M., Ntolkeras, G., Grant, P. E., Madsen, J. R., Stufflebeam, S. M., Pearl, P. L., & Papadelis, C. (2021). Noninvasive Mapping of Ripple Onset Predicts Outcome in Epilepsy Annals of neurology, 89(5), 911–925. https://doi.org/10.1002/ana.26066.
- Samanta, D., Singh, R., Gedela, S., Scott Perry, M., & Arya, R. (2021). Underutilization of epilepsy surgery: Part II: Strategies to overcome barriers. Epilepsy & behavior : E&B, 117, 107853. https://doi.org/10.1016/j.yebeh.2021.107853.
- Bain, J. M., Thornburg, O., Pan, C., Rome-Martin, D., Boyle, L., Fan, X., Devinsky, O., Frye, R., Hamp, , Keator, C. G., LaMarca, N. M., Maddocks, A., Madruga-Garrido, M., Niederhoffer, K. Y., Novara, F., Peron, A., Poole-Di Salvo, E., Salazar, R., Skinner, S. A., Soares, G., Goldman, S., Chung, W. K. (2021). Detailed Clinical and Psychological Phenotype of the X-linked HNRNPH2- Related Neurodevelopmental Disorder. Neurology. Genetics, 7(1), e551. https://doi.org/10.1212/NXG.0000000000000551.
- Samanta, D., Ostendorf, A. P., Willis, E., Singh, R., Gedela, S., Arya, R., & Scott Perry, M. (2021). Underutilization of epilepsy surgery: Part I: A scoping review of barriers. Epilepsy & behavior : E&B, 117, 107837. https://doi.org/10.1016/j.yebeh.2021.107837.
- Styliadis, C., Leung, R., Özcan, S., Moulton, E. A., Pang, E., Taylor, M. J., & Papadelis, C. (2021). Atypical spatiotemporal activation of cerebellar lobules during emotional face processing in adolescents with autism. Human brain mapping, 42(7), 2099–2114. https://doi.org/10.1002/hbm.25349.
- Shandley, S., Capilouto, G., Tamilia, E., Riley, D. M., Johnson, Y. R., & Papadelis, C. (2021). Abnormal Nutritive Sucking as an Indicator of Neonatal Brain Injury. Frontiers in pediatrics, 8, https://doi.org/10.3389/fped.2020.599633.
- Sullivan, J., Perry, M. S., Wheless, J. W., Galer, B., & Gammaitoni, A. (2021). Fenfluramine responder analyses and numbers needed to treat: Translating epilepsy trial data into clinical European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 31, 10–14. https://doi.org/10.1016/j.ejpn.2021.01.005.
- Pearl, P. L., DiBacco, M. L., Papadelis, C., Opladen, T., Hanson, E., Roullet, J. B., & Gibson, K. M. (2021). Succinic Semialdehyde Dehydrogenase Deficiency: Review of the Natural History Journal of child neurology, 883073820981262. Advance online publication. https://doi.org/10.1177/0883073820981262.
- Papadelis, C. (2021). MEG systems for young children and recent developments of pediatric MEG. In H., & Roberts, T. P. L. (Ed.). Advances in magnetic resonance technology and applications (2, 329-342). Academic Press.
- Perry, M.S., & Papadelis, C. (2021). Clinical correlation advised: Measuring functional connectivity in Epilepsy Currents 21(1), 30-32. https://doi.org/10.1177/1535759720975436.
Abstract, Posters, and Conference Presentations:
- Perry, M.S., Arrowood, R., Wong-Kisiel, L., Singh, R., McNamara, N., Fedak Romanowski, E., Grinspan, Z., Eschbach, K., Alexander, A., McGoldrick, P., Wolf, S., Marashly, A., Nangia, S., Bolton, J., Shrey, D., Karia, S., Tatachar, P., Ostendorf, A.P., Gedela, S., Koop, J., Ciliberto, M., Reddy, S., Manuel, C., Gonzalez-Giraldo, E., Bernardo, D., Coryell, J., & Depositario-Cabacar, D. (2021, December 02-06). Racial and ethnic disparities in pediatric epilepsy surgery [Poster]. 2021 Annual Meeting of the American Epilepsy Society, Chicago, Illinois, USA.
- Rijal, S., Corona, L.,Alexandrakis, G., Tamilia, E., Madsen, J. R., Pearl, P. L., Papadelis, C. (2021, December 02-06). Functional connectivity of gamma activity quantifies brain epileptogenicity in children with refractory epilepsy [Abstract, Poster]. 2021 Annual Meeting of the American Epilepsy Society, Chicago, Illinois, USA.
- Jahromi, S., Matarrese, M. A. G., Fabbri, L., Tamilia, E., Scott Perry, M., Madsen, J. R., Pearl, P. L., Papadelis, C. (2021, December 02-06). Overlapping onset of spike and ripple propagations is a more specific biomarker of the epileptogenic zone than fast ripples. [Abstract, Poster]. 2021 Annual Meeting of the American Epilepsy Society, Chicago, Illinois, USA.
- Corona, L., Tamilia, E., Scott Perry, M., Madsen, J. R., Stufflebeam, S., Pearl, P. L., Papadelis, C. (2021, December 02-06). Functional connectivity estimated through virtual implantation predicts surgical outcome in children with epilepsy [Abstract, Poster]. 2021 Annual Meeting of the American Epilepsy Society, Chicago, Illinois, USA. * Young Investigator Award
- Tamilia, E. (2021, December 02-06). Combining brain connectivity and excitability to plan epilepsy surgery in children: A new tool to get the most from intracranial EEG independently of traditional epilepsy biomarkers [Abstract, Poster]. 2021 Annual Meeting of the American Epilepsy Society, Chicago, Illinois, USA.
- Iandolo, G. (2021, December 02-06). Changes in the functional brain network of children under-going repeated epilepsy surgery: An EEG source connectivity study [Abstract, Poster]. 2021 Annual Meeting of the American Epilepsy Society, Chicago, Illinois, USA.
- Ricci, L.,Matarrese, M., Peters, J. M., Tamilia, E., Madsen, J. R., Pearl, P. L., Papadelis, C. (2021, December 02-06). Electric source imaging on ictal conventional scalp EEG delineates seizure onset and predicts surgical outcomes in children with epilepsy [Abstract, Poster]. 2021 Annual Meeting of the American Epilepsy Society, Chicago, Illinois, USA.
- Matarrese, M., Loppini, A., Tamilia, E., Perry, M. S., Pearl, P. L., Madsen, J. R., Filippi, S., Papadelis, (2021, December 02-06). Onset of spike propagation identifies the epileptogenic zone in children with refractory epilepsy: a multimodal electric source and diffusion imaging study [Abstract, Poster]. 2021 Annual Meeting of the American Epilepsy Society, Chicago, Illinois, USA. * Young Investigator Award
- Fabbri, L., Jahromi, S., Scott Perry, M., Tamilia, E., Madsen, J. R., Pearl, P. L., Papadelis, C. (2021, December 02-06). Phase amplitude coupling between spikes and ripples identifies the epileptogenic zone in children with drug resistant epilepsy [Abstract, Poster]. 2021 Annual Meeting of the American Epilepsy Society, Chicago, Illinois, USA.
- Ntolkeras, G. (2021, December 02-06). Non-invasive electrophysiological signatures of the epileptogenic zone using conventional scalp EEG in children with focal drug-resistant epilepsy [Abstract, Poster]. 2021 Annual Meeting of the American Epilepsy Society, Chicago, Illinois, USA.
- Jahromi, S.,Matarrese, M., Tamilia, E., Perry, M. S., Madsen, J. R., Pearl, P. L., & Papadelis, C. (2021). Mapping Propagation of Interictal Spikes, Ripples, and Fast Ripples in Intracranial EEG of Children with Refractory Epilepsy. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2021, 194–197. https://doi.org/10.1109/EMBC46164.2021.9630250.
- King, F. K., Scott Perry, M., Papdelis, C., Cooper, C. M. (2021, November 13-17). Emotional conflict processing in adolescents with epilepsy: a pilot magnetoencephalography study [Abstract]. Society for Neuroscience’s 50th Annual Meeting, Chicago, Illinois, USA.
- Corona, L., Tamilia, E., Madsen, J. R., Stufflebeam, S. M., Pearl, P. L., & Papadelis, C. (2021). Mapping Functional Connectivity of Epileptogenic Networks through Virtual Implantation. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2021, 408–411. https://doi.org/10.1109/EMBC46164.2021.9629686.
- Matarrese, M., Loppini, A., Jahromi, S., Tamilia, E., Fabbri, L., Madsen, J. R., Pearl, P. L., Filippi, S., & Papadelis, C. (2021). Electric Source Imaging on Intracranial EEG Localizes Spatiotemporal Propagation of Interictal Spikes in Children with Epilepsy. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Annual International Conference, 2021, 2668–2671. https://doi.org/10.1109/EMBC46164.2021.9630246.
Abstract, Posters, and Conference Presentations from Collaborators:
- (2021, December 02-06). Comparing characteristics and outcome of palliative and definitive pediatric epilepsy surgery patients using the Pediatric Epilepsy Research Consortium (PERC) surgery database [Poster]. 2021 Annual Meeting of the American Epilepsy Society, Chicago, Illinois, USA.
- (2021, December 02-06). Death in children with seizures and epilepsy in the Pediatric Epilepsy Learning Healthcare System [Poster]. 2021 Annual Meeting of the American Epilepsy Society, Chicago, Illinois, USA.
- (2021, December 02-06). COVID-19 Vaccination and Dravet Syndrome [Poster]. 2021 Annual Meeting of the American Epilepsy Society, Chicago, Illinois, USA.
- (2021, December 02-06). SWALLOWTAIL: An open-label extension (OLE) study for patients with Dravet syndrome (DS) who previously participated in studies of STK- 001 [Poster]. 2021 Annual Meeting of the American Epilepsy Society, Chicago, Illinois, USA
- (2021, December 02-06). The ENVISION Study: An international, prospective natural history study in young children with SCN1A+ Dravet syndrome [Poster]. 2021 Annual Meeting of the American Epilepsy Society, Chicago, Illinois, USA.
- (2021, December 02-06). Initial success and impact of building a collaborative among pediatric neuropsychologists [Poster]. 2021 Annual Meeting of the American Epilepsy Society, Chicago, Illinois, USA.
- (2021, December 02-06). Molecular diagnosis from genetic testing guides clinical management of epilepsy and helps improve patient outcomes [Poster]. 2021 Annual Meeting of the American Epilepsy Society, Chicago, Illinois, USA.
- (2021, December 02-06). Fenfluramine (Fintepla) significantly reduces day-to-day seizure burden by increasing seizure-free days: A time-to-event analysis of a phase 3 study in Dravet syndrome [Poster]. 2021 Annual Meeting of the American Epilepsy Society, Chicago, Illinois, USA.
- (2021, December 02-06). Oxcarbazepine use and the risk of infantile spasms among children with epilepsy [Poster]. 2021 Annual Meeting of the American Epilepsy Society, Chicago, Illinois, USA.
- (2021, December 02-06). Seizure related outcomes with real-world use of cannabidiol (CBD) in Lennox-Gastaut syndrome (LGS) and Dravet syndrome (DS): BECOME, a caregiver study [Poster]. 2021 Annual Meeting of the American Epilepsy Society, Chicago, Illinois, USA.
- (2021, December 02-06). Non-seizure related outcomes with real-world use of cannabidiol (CBD) in Lennox-Gastaut syndrome (LGS) and Dravet syndrome (DS): BECOME, a caregiver survey [Poster]. 2021 Annual Meeting of the American Epilepsy Society, Chicago, Illinois, USA.
- (2021, December 02-06). Epilepsy surgery in tuberous sclerosis complex: Results from the Pediatric Epilepsy Research Consortium epilepsy surgery database [Poster]. 2021 Annual Meeting of the American Epilepsy Society, Chicago, Illinois, USA.
- (2021, December 02-06). Seizure outcome of MRI-guided laser interstitial thermal therapy compared to resective epilepsy surgery: A propensity matched cohort study [Poster]. 2021 Annual Meeting of the American Epilepsy Society, Chicago, Illinois, USA.
- (2021, December 02-06). Responsive neurostimulation in pediatric refractory epilepsy: Findings from the PERC (Pediatric Epilepsy Research Consortium,) epilepsy surgery subgroup [Poster]. 2021 Annual Meeting of the American Epilepsy Society, Chicago, Illinois, USA.
Patents:
- Loddenkemper, T., Jackson, M., Touserkani, F.M., Tamilia, E., & Papadelis, C. (2021). Seizure prediction using cardiovascular features (U.S. Patent No. 10,959,662). U.S. Patent and Trademark Office. https://patft.uspto.gov/netacgi/nph- Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch- html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=%22seizure+prediction+using+cardiovascular +features%22&OS=.
2020
Publications in Scientific Journals:
- Rodger, C., Flex, E., Allison, R. J., Sanchis-Juan, A., Hasenahuer, M. A., Cecchetti, S., French, C. E., Edgar, J. R., Carpentieri, G., Ciolfi, A., Pantaleoni, F., Bruselles, A., Genomics England Research Consortium, Onesimo, R., Zampino, G., Marcon, F., Siniscalchi, E., Lees, M., Krishnakumar, D., McCann, E., Yosifova, D., Jarvis, J., Kruer, M. C., Marks, W., Campbell, J., Allen, L. E., Gustincich, , Raymond, F. L., Tartaglia, M., Reid, E. (2020). De Novo VPS4A Mutations Cause Multisystem Disease with Abnormal Neurodevelopment. American journal of human genetics, 107(6), 1129– 1148. https://doi.org/10.1016/j.ajhg.2020.10.012.
- Rose, J., Papadelis, C., & Gaebler-Spira, D. (2020). Editorial: Neurologic Correlates of Motor Function in Cerebral Palsy: Opportunities for Targeted Treatment. Frontiers in human neuroscience, 14, https://doi.org/10.3389/fnhum.2020.615397.
- Alexander, R., Aragón, O. R., Bookwala, J., Cherbuin, N., Gatt, J. M., Kahrilas, I. J., Kästner, N., Lawrence, A., Lowe, L., Morrison, R. G., Mueller, S. C., Nusslock, R., Papadelis, C., Polnaszek, K. , Helene Richter, S., Silton, R. L., & Styliadis, C. (2021). The neuroscience of positive emotions and affect: Implications for cultivating happiness and wellbeing. Neuroscience and biobehavioral reviews, 121, 220–249. https://doi.org/10.1016/j.neubiorev.2020.12.002.
- Tidball, A. M., Lopez-Santiago, L. F., Yuan, Y., Glenn, T. W., Margolis, J. L., Clayton Walker, J., Kilbane, G., Miller, C. A., Martina Bebin, E., Scott Perry, M., Isom, L. L., & Parent, J. M. (2020). Variant- specific changes in persistent or resurgent sodium current in SCN8A-related epilepsy patient- derived neurons. Brain : a journal of neurology, 143(10), 3025–3040. https://doi.org/10.1093/brain/awaa247.
- El Atrache, R., Tamilia, E., Mohammadpour Touserkani, F., Hammond, S., Papadelis, C., Kapur, K., Jackson, M., Bucciarelli, B., Tsuboyama, M., Sarkis, R. A., & Loddenkemper, T. (2020). Photoplethysmography: A measure for the function of the autonomic nervous system in focal impaired awareness seizures. Epilepsia, 61(8), 1617–1626. https://doi.org/10.1111/epi.16621.
- Gaetz, W., Papadelis, C., & Wilson T. W. (2020). Clinical motor mapping with In Papanicolaou, A. C., Roberts, T. P. L., & Wheless, J. W. (Ed.). Fifty years of magnetoencephalography: Beginnings, technical advances, and applications, 211. Oxford University Press.
- Mohammadpour Touserkani, F., Tamilia, E., Coughlin, F., Hammond, S., El Atrache, R., Jackson, M., Bendsen-Jensen, M., Kim, B., Connolly, J., Manganaro, S., Papadelis, C., Kapur, K., & Loddenkemper, T. (2020). Photoplethysmographic evaluation of generalized tonic-clonic Epilepsia, 61(8), 1606–1616. https://doi.org/10.1111/epi.16590.
- Richard, E. M., Bakhtiari, S., Marsh, A. P. L., Kaiyrzhanov, R., Wagner, M., Shetty, S., Pagnozzi, A., Nordlie, S. M.,…Marks, W. A.,…& Kruer, M. C. (2020). Bi-allelic variants in SPATA5L1 lead to intellectual disability, spastic-dystonic cerebral palsy, epilepsy, and hearing loss. The American journal of human genetics: Cell press, 108(10), 2006-2016. https://doi.org/10.1016/j.ajhg.2021.08.003.
- Papadelis, C., & Chen, Y. H. (2020). Pediatric Magnetoencephalography in Clinical Practice and Neuroimaging clinics of North America, 30(2), 239–248. https://doi.org/10.1016/j.nic.2020.02.002.
- Miller, I., Scheffer, I. E., Gunning, B., Sanchez-Carpintero, R., Gil-Nagel, A., Perry, M. S., Saneto, R. P., Checketts, D., Dunayevich, E., Knappertz, V., & GWPCARE2 Study Group (2020). Dose-Ranging Effect of Adjunctive Oral Cannabidiol vs Placebo on Convulsive Seizure Frequency in Dravet Syndrome: A Randomized Clinical Trial. JAMA neurology, 77(5), 613–621. https://doi.org/10.1001/jamaneurol.2020.0073.
- Perry, M. S. (2020). You Can Teach an Old Drug New Tricks. Epilepsy currents, 20(4), 193–195. https://doi.org/10.1177/1535759720923035.
- Grinspan, Z. M., Mytinger, J. R., Baumer, F. M., Ciliberto, M. A., Cohen, B. H., Dlugos, D. J., Harini, C., Hussain, S. A., Joshi, S. M., Keator, C. G., Knupp, K. G., McGoldrick, P. E., Nickels, K. C., Park, J. T., Pasupuleti, A., Patel, A. D., Shahid, A. M., Shellhaas, R. A., Shrey, D. W., Singh, R. K., Wolf, S. M., Yozawitz, E. G., Yuskaitis, C. J., Waugh, J. L., Pearl, P. L. (2020). Management of Infantile Spasms During the COVID-19 Pandemic. Journal of child neurology, 35(12), 828–834. https://doi.org/10.1177/0883073820933739.
- Grinspan, Z. M., Mytinger, J. R., Baumer, F. M., Ciliberto, M. A., Cohen, B. H., Dlugos, D. J., Harini, C., Hussain, S. A., Joshi, S. M., Keator, C. G., Knupp, K. G., McGoldrick, P. E., Nickels, K. C., Park, J. T., Pasupuleti, A., Patel, A. D., Pomeroy, S. L., Shahid, A. M., Shellhaas, R. A., Shrey, D. W., Singh, R. , Wolf, S. M., Yozawitz, E. G., Yuskaitis, C. J., Waugh, J. L., Pearl, P. L., Child Neurology Society (Practice Committee and Executive Board) and the Pediatric Epilepsy Research Consortium (Infantile Spasms Special Interest Group and Steering Committee) (2020). Crisis Standard of Care: Management of Infantile Spasms during COVID-19. Annals of neurology, 88(2), 215–217. https://doi.org/10.1002/ana.25792.
- Perry M. S. (2020). New and Emerging Medications for Treatment of Pediatric Epilepsy. Pediatric neurology, 107, 24–27. https://doi.org/10.1016/j.pediatrneurol.2019.11.008.
- Arocho-Quinones, E. V., Lew, S. M., Handler, M. H., Tovar-Spinoza, Z., Smyth, M., Bollo, R., Donahue, ,Perry, M. S., Levy, M. L., Gonda, D., Mangano, F. T., Storm, P. B., Price, A. V., Couture, D. E., Oluigbo, C., Duhaime, A. C., Barnett, G. H., Muh, C. R., Sather, M. D., Fallah, A., Wang, A. C., Bhatia, S., Patel, K., Tarima, S., Graber, S., Huckins, S., Hafez, D. M., Rumalla, K., Bailey, L., Shandley, S., Roach, A., Alexander, E., Jenkins, W., Tsering, D., Price, G., Meola, A., Evanoff, W., Thompson, E. M., Brandmeir, N.; Pediatric Stereotactic Laser Ablation Workgroup (2020). Magnetic resonance-guided stereotactic laser ablation therapy for the treatment of pediatric brain tumors: a multi-institutional retrospective study. Journal of neurosurgery. Pediatrics, 1–9. Advance online publication. https://doi.org/10.3171/2020.1.PEDS19496.
- Turner, A. L., Shandley, S., Miller, E., Perry, M. S., & Ryals, B. (2020). Intranasal Ketamine for Abortive Migraine Therapy in Pediatric Patients: A Single-Center Review. Pediatric neurology, 104, 46–53. https://doi.org/10.1016/j.pediatrneurol.2019.10.007.
- Tamilia, E., Dirodi, M., Alhilani, M., Grant, P. E., Madsen, J. R., Stufflebeam, S. M., Pearl, P. L., & Papadelis, C. (2020). Scalp ripples as prognostic biomarkers of epileptogenicity in pediatric Annals of clinical and translational neurology, 7(3), 329–342. https://doi.org/10.1002/acn3.50994.
- Alhilani, M., Tamilia, E., Ricci, L., Ricci, L., Grant, P. E., Madsen, J. R., Pearl, P. L., & Papadelis, C. (2020). Ictal and interictal source imaging on intracranial EEG predicts epilepsy surgery outcome in children with focal cortical dysplasia. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 131(3), 734–743. https://doi.org/10.1016/j.clinph.2019.12.408.
- Perry M. S. (2020). Age Is Just a Number: Adults Deserve the Same Access to Genetic Testing as Epilepsy currents, 20(1), 14–15. https://doi.org/10.1177/1535759719887695.
- Johnson, B. V., Kumar, R., Oishi, S., Alexander, S., Kasherman, M., Vega, M. S.,…Perry, M. S.,… Koenig, M. K., Keegan, C. E., Schuette, J. L., Asher, S., Perilla-Young, Y., Smith, L. D., Rosenfeld, & Jolly, L. A. (2020). Partial Loss of USP9X Function Leads to a Male Neurodevelopmental and Behavioral Disorder Converging on Transforming Growth Factor β Biological psychiatry, 87(2), 100–112. https://doi.org/10.1016/j.biopsych.2019.05.028.
- Marks, W. A., Acord, S., Bailey, L., Honeycutt, J. (2020). Neuromodulation in childhood onset dystonia : evolving role of deep brain stimulation. Current physical medicine and rehabilitation reports,8, 37–43.
Abstracts, Posters, and Conference Presentations:
- Corona, L., Tamilia, E., Taffoni, F., Madsen, J. R., Stufflebeam, S., Pearl, P. L., Papadelis, C. (2020, December 04-08). Mapping functional connectivity of epileptogenic networks with virtual intracranial sensors [Abstract, Poster]. 74th Annual American Epilepsy Society Meeting, Virtual * selected to present in the Pediatric Highlight session.
- Fabbri, L.,Jahromi, S., Tamilia, E., Khokhar, M. A., Rhodes, E., Perry, M. S., Madsen, J. R., Pearl, P. L., Papadelis, C. (2020, December 04-08). Spikes overlapping on high frequency oscillations delineate the seizure onset and predict surgical outcome in children with epilepsy [Abstract]. 74th Annual American Epilepsy Society Meeting, Virtual Conference.
- Rijal, S., Tamilia, E., Jahromi, S., Baset, N., Alexandrakis, G., Scott Perry, M., Pearl, P. L., Madsen, J. , Papadelis, C. (2020, December 04-08). Functional connectivity on spikes with ripples delineates seizure onset and predicts surgical outcome in children with epilepsy [Abstract]. 74th Annual American Epilepsy Society Meeting, Virtual Conference.
- Newell, G., Papadelis, C., Shandley, S., Wong-Kisiel, L., McNamara, N., Fedak Romanowski, E., Reddy, S., Patel, S., Ciliberto, M., Nangia, S., Grinspan, Z., Depositario-Cabacar, D., Singh, R., Marashly, A., Shrey, D., Karia, S., Ostendorf, A., Tatachar, P., Sannagowdara, K., Lew, S., Chapman, K., Alexander, A., Wolf, S., McGoldrick, P., Bolton, J., Coryell, J., Perelman, M., Gedela, , Perry, M. S. (2020, December 04-08). Factors leading to >2 antiseizure medication trials prior to epilepsy surgery referral in children [Abstract]. 74th Annual American Epilepsy Society Meeting, Virtual Conference.
- Wong-Kisiel, L., Alexander, A., Tatachar, P., Reddy, S., Bolton, J., Marashly, A., Depositario-Cabacar, , Romanowski, E., Shrey, D., McNamara, N., Karia, S., Nangia, S., Patel, S., Singh, R., Shandley, S., Perry, M. (2020, December 04-08). Utilization of diagnostic modalities in pediatric epilepsy surgery: the pediatric epilepsy research consortium epilepsy surgery experience [Poster]. 74th Annual American Epilepsy Society Meeting, Virtual Conference.
- Singh, R. K., Perry, M. S., Wong-Kisiel, L., Shandley, S., Grinspan, Z., Depositario-Cabacar, D., Ciliberto, M., Chapman, K., Tatachar, P., Romanowski, E., Alexander, A., Bolton, J., Coryell, J., Gedela, S., Karia, S., Lew, S., Marashly, A., McGoldrick, P., McNamara, N., Nangia, S., Ostendorf, , Perelman, M., Reddy, S., Patel, S., Sannagowdara, K., Shrey, D., Wolf, S. (2020, December 04- 08). Initial vs. repeat epilepsy surgery evaluation for children in the US: findings from the PERC (Pediatric Epilepsy Research Consortium) epilepsy surgery subgroup [Poster]. 74th Annual American Epilepsy Society Meeting, Virtual Conference.
- Papadelis, C., Ntolkeras, G., DiBacco, M. L., Alhilani, M., Nunes, D., Roullet, J-B, Gibson, K. M., Pearl, L. (2020). Gamma suppression on somatosensory evoked potentials in patients with succinic semialdehyde dehydrogenase deficiency (SSADHD), a hyper-GABAergic condition [Virtual Conference]. 16th International Child Neurology Congress / 49th Annual Child Neurology Society Meeting.
- Newell, G.,Papadelis, C., Malik, S., Keator, C., Shahani, D., Shandley, S., Scott Perry, M. (2020, October 12-23). Characteristics of children with epilepsy failing more than two antiseizure medications before referral for surgical evaluation [Abstract]. 16th International Child Neurology Congress / 49th Annual Child Neurology Society Meeting, Virtual Conference.
- Newell, G., Shandley, S., Papadelis, C., Perry, M. S. (2020). Characteristics of children with epilepsy failing more than 2 AEDs prior to surgical referral. Child Neurology Society Meeting, San Diego, California, USA.
- Perry, M. S., Wirrell, E., Burkholder, D., Galer, B., Gammaitoni, A. (2020). Real-world experience with ZX008 (Fenfluramine HCl) for the treatment of seizures in Dravet syndrome: initial report from United States expanded access program. American Academy of Neurology Annual Meeting, Toronto, Ontario, Canada. * cancelled due to COVID-19 pandemic.
- Patel, A., Chin, R., Mitchell, W., Perry, M. S., Weinstock, A., Checketts, D., Dunayevich, E. (2020). Long-term safety and efficacy of cannabidiol (CBD) treatment in patients with Lennox Gastaut syndrome (LGS): 3-year results of an open-label extension (OLE) trial (GWPCARE5). American Academy of Neurology Annual Meeting, Toronto, Ontario, Canada. * cancelled due to COVID-19
- Alhilani, M., Tamilia, E., Ricci, L., Grant, P. E., Alter, A., Peters, J. M., Pearl, P. L., Madsen, J. R., Papadelis, C. (2020, March 11-15). Clinical utility of electric source imaging on intracranial electroencephalography in children with focal cortical dysplasia [Poster]. European Congress of Radiology (ECR) 2020 Annual Congress, Vienna, Austria, * 2020 ECR “Invest in the Youth” Award.
2019
Publications in Scientific Journals:
- Dash, D., Ferrari, P., Malik, S., Montillo, A., Maldjian, J. A., & Wang, J. (2019). Determining the Optimal Number of MEG Trials: A Machine Learning and Speech Decoding Perspective. Brain informatics : international conference, BI 2018, Arlington, TX, USA, December 7-9, 2018, International Conference on Brain Informatics (2018 : Arlington, Tex.), 11309, 163– 172. https://doi.org/10.1007/978-3-030-05587-5_16.
- Tamilia, E., Parker, M. S., Rocchi, M., Taffoni, F., Hansen, A., Grant, P. E., & Papadelis, C. (2019). Nutritive sucking abnormalities and brain microstructural abnormalities in infants with established brain injury: a pilot study. Journal of perinatology : official journal of the California Perinatal Association, 39(11), 1498–1508. https://doi.org/10.1038/s41372-019-0479-6.
- Dirodi, M., Tamilia, E., Grant, P. E., Madsen, J. R., Stufflebeam, S. M., Pearl, P. L., & Papadelis, C. (2019). Noninvasive localization of high-frequency oscillations in children with epilepsy: Validation against intracranial gold-standard. 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), pp. 1555-1558, IEEE, Berlin, Germany. https://doi.org/10.1109.EMBC.2019.8857793.
- Berg, A. T., Wusthoff, C., Shellhaas, R. A., Loddenkemper, T., Grinspan, Z. M., Saneto, R. P., Knupp, K. , Patel, A., Sullivan, J. E., Kossoff, E. H., Chu, C. J., Massey, S., Valencia, I., Keator, C., Wirrell, E. C., Coryell, J., Millichap, J. J., & Gaillard, W. D. (2019). Immediate outcomes in early life epilepsy: A contemporary account. Epilepsy & behavior : E&B, 97, 44–50. https://doi.org/10.1016/j.yebeh.2019.05.011.
- Perry M. S. (2019). Don't Fear the Reefer-Evidence Mounts for Plant-Based Cannabidiol as Treatment for Epilepsy. Epilepsy currents, 19(2), 93–95. https://doi.org/10.1177/1535759719835671.
- Reynhout, S., Jansen, S., Haesen, D., van Belle, S., de Munnik, S. A., Bongers, E., Schieving, J. H., Marcelis, C., Amiel, J., Rio, M., Mclaughlin, H., Ladda, R., Sell, S., Kriek, M., Peeters-Scholte, C., Terhal, P. A., van Gassen, K. L., Verbeek, N., Henry, S., Scott Schwoerer, J., Malik, S., Revencu, N., Ferreira, C. R., Macnamara, E., Braakman, H. M. H., Brimble, E., Ruzhnikov, M. R. Z., Wagner, M., Harrer, P., Wieczorek, D., Kuechler, A., Tziperman, B., Barel, O., A de Vries, B. A., Cordon, C. T., Janssens, V., Vissers, L. E. L. M. (2019). De Novo Mutations Affecting the Catalytic Cα Subunit of PP2A, PPP2CA, Cause Syndromic Intellectual Disability Resembling Other PP2A-Related Neurodevelopmental Disorders. American journal of human genetics, 104(1), 139–156. https://doi.org/10.1016/j.ajhg.2018.12.002.
Abstracts, Posters, and Conference Presentations:
- El Atrache, R., Tamilia, E., Hammond, S., Mohammadpour Touserkani, F., Papadelis, C., Kapur, K., Jackson, M., Ufongene, C., Schubach, S., Bucciarelli, B., Tsuboyama, M., Sarkis, R., Loddenkemper, T. (2019, December 06-10). Photoplethysmography detects blood volume pressure changes in the pre-ictal and post-ictal periods in patients with focal impaired awareness seizures [Poster]. 73rd Annual American Epilepsy Society Meeting, Baltimore, Maryland, USA. * 2019 Grass Foundation Young Investigator Award.
- Ricci, L., Tamilia, T., Alhilani, M., Grant, P. E., Alter, A., Madsen, J. R., Peters, J. M., Pearl, P. L., Papadelis, C. (2019, December 06-10). Electrical source imaging of seizure onset zone with conventional 20-channel EEG is predictive of surgical outcome in children with epilepsy [Poster]. 73rd Annual American Epilepsy Society Meeting, Baltimore, Maryland, USA. * Selected to be presented as a talk in the pediatric highlights of the conference.
- Tamilia, E., Dirodi, M., Madsen, J. R., Stufflebeam, S. M., Pearl, P. L., Papadelis, C. (2019, December 06-10). Pre-surgical electric and magnetic source imaging of scalp-recorded ripples in children with epilepsy: concordance with intracranial EEG and epileptogenic zone [Poster]. 73rd Annual American Epilepsy Society Meeting, Baltimore, Maryland, USA. * 2019 Grass Foundation Young Investigator Award.
- Alhilani, M., Tamilia, E., Ricci, L., Grant, P. E., Alter, A., Peters, J. M., Pearl, P. L., Madsen, J. R., Papadelis, C. (2019, December 06-10). Clinical utility of electric source imaging on intracranial electroencephalography in children with focal cortical dysplasia [Poster]. 73rd Annual American Epilepsy Society Meeting, Baltimore, Maryland, USA.
- Ntolkeras, G., Tamilia, T., Alhilani, M., Madsen, J. R., Stufflebeam, S., Pearl, P. L., Papadelis, C. (2019, December 06-10). Pre-surgical ability of magnetic and electric source imaging to localize the epileptogenic zone in children with focal cortical dysplasia [Poster]. 73rd Annual American Epilepsy Society Meeting, Baltimore, Maryland, USA.
- Singh, R., Wong-Kisiel, L., Perry, M. S., Shandley, S., McNamara, N., Grinspan, Z., Chapman, K., McGoldrick, P., Marashly, A., Wolf, S., Nangia, S., Bolton, J., Shrey, D., Skjei, K., Romanowski, E., Tatachar, P., Osterndorf, A., Gedela, S. (2019, December). Characteristics of patients referred for pediatric epilepsy surgery evaluation in the US: early findings from the PERC (pediatric epilepsy research consortium) epilepsy surgery subgroup. 73rd Annual American Epilepsy Society Meeting, Baltimore, Maryland, USA.
- Perry M. S., Wong-Kisiel, L., Singh, R., Shandley, S., McNamara, N., Grinspan, Z., Chapman, K., McGoldrick, P., Marashly, A., Wolf, S., Nangia, S., Bolton J., Shrey, D., Skjei, K., Romanowski, E., Tatachar, P., Osterndorf, A., Gedela, S. (2019, December). Time to referral for epilepsy surgery evaluation is longer in older children with intractable epilepsy – a potential opportunity for 73rd Annual American Epilepsy Society Meeting, Pediatric Epilepsy Highlights Session, Baltimore, Maryland, USA.
- Schafer, P., Farrell, K., Kakacek, J., Owens, S., Schultz, R., Shah, A., Hueneke, S., Joshi, S., Perry, M. S., Newborn-Palmer, L., Fain, D., McPhillips, A., Nasuta, M., Doss, J., Cushner-Weinstein, S., Parsupuleti, A., Rodecki, L. (2019). Managing students with seizures ECHO: the importance of school nurses. 73rd Annual American Epilepsy Society Meeting, Baltimore, Maryland, USA.
- Sullivan, J., Devinsky, O., Galer, B., Farfel, G., Haney, D., Perry, M. S., Auvin, S., Gil-Nagel, A., Gammaitoni A. (2019). ZX008 (Fenfluramine Hydrochloride oral solution) reduced seizure burden by significantly increasing number of seizure-free days and time between seizures in patients with Dravet syndrome. 73rd Annual American Epilepsy Society Meeting, Baltimore, Maryland,
- Segal, E., Miller, I., Perry, M. S., Brunklaus, A., Sameer, Z., O’Donnell, P., Tagliatela, S., Maru, B., Seda, J., Kilian, R., Gioia, G. A., Berl, M. M. (2019). Proposed design for a natural history study of SCN1A-positive (SCN1A+) Dravet syndrome. 73rd Annual American Epilepsy Society Meeting, Baltimore, Maryland, USA.
- Miller, I., Dlugos, D., Segal, E., Giola, G., Berl, M., O’Donnell, P., Tagliatela, S. M., Seda, J., Kilian, R., Perry, M. S. (2019). From gene replacement to gene regulation: developing a disease modifying AAV gene therapy vector for SCN1A-positive (SCN1A+) Dravet syndrome. 73rd Annual American Epilepsy Society Meeting, Baltimore, Maryland, USA.
- Patel, A. D., Chin, R. F., Mitchell, W., Perry, M. S., Weinstock, A., Checketts, D., Dunayevich, E. (2019). Long-term safety and efficacy of add-on cannabidiol in patients with Lennox-Gastaut syndrome: 3-year results of an open-label extension trial (GWPCARE5). 73rd Annual American Epilepsy Society Meeting, Baltimore, Maryland, USA.
- Schneider, A. L., Myers, C., Muir, A. M., Calvert, S., Basinger, A., Perry, M. S., Rodan, L., Helbig, K. L., Chambers, C., Gorman, K., Berkovic, S., Mefford, H. C., Scheffer, I. E. (2019). Pathogenic variants in FBXO28 cause developmental and epileptic encephalopathy with profound impairment and movement disorders. 73rd Annual American Epilepsy Society Meeting, Baltimore, Maryland, USA.
- Perry, M. S., Patel, A., Gil-Nagel, A., Chin, R., Mitchel, W., Weinstock, A., Roberts, C., Whyte, L., Vanlandinham, K. (2019, October 23-26). Long-term safety and efficacy of add-on cannabidiol (CBD) treatment in patients with Lennox Gastaut Syndrome in an open-label extension trial (GWPCARE5). Child Neurology Society Meeting, Charlotte, North Carolina, USA.
- Perry, M. S., Miller, I., Scheffer, I., Gunning, B., Sanchez-Carpintero, R., Gil-Nagel, A., Saneto, R., Checketts, D., Whyte, L., Dunayevich, E., Knappertz, V. (2019, October 23-26). Cannabidiol (10 and 20 mg/kg/d) significantly reduces convulsive seizure frequency in Dravet syndrome: results of a phase 3 trial (GWPCARE2). Child Neurology Society Meeting, Charlotte, North Carolina, USA.
- Perry M. S., Wong-Kisiel, L., Singh, R., McGoldrick, P., Wolf, S., Mohamed, I., McNamara, N., Romanowski, E., Shrey, D., Chapman, K., Bolton, J., Marashly, A., Clareke, D., Akman, C., Grinspan, Z., Gedela, S. (2019, October 23-26). Collaborating to improve epilepsy surgical care in children: the pediatric epilepsy research consortium (PERC) surgery subgroup. Child Neurology Society Meeting, Charlotte, North Carolina, USA.
2018
Publications in Scientific Journals:
- Coryell, J., Gaillard, W. D., Shellhaas, R. A., Grinspan, Z. M., Wirrell, E. C., Knupp, K. G., Wusthoff, C. , Keator, C., Sullivan, J. E., Loddenkemper, T., Patel, A., Chu, C. J., Massey, S., Novotny, E. J., Jr, Saneto, R. P., & Berg, A. T. (2018). Neuroimaging of Early Life Epilepsy. Pediatrics, 142(3), e20180672. https://doi.org/10.1542/peds.2018-0672.
- Berg, A. T., Chakravorty, S., Koh, S., Grinspan, Z. M., Shellhaas, R. A., Saneto, R. P., Wirrell, E. C., Coryell, J., Chu, C. J., Mytinger, J. R., Gaillard, W. D., Valencia, I., Knupp, K. G., Loddenkemper, T., Sullivan, J. E., Poduri, A., Millichap, J. J., Keator, C., Wusthoff, C., Ryan, N., Dobyns, W. B., Hedge, (2018). Why West? Comparisons of clinical, genetic and molecular features of infants with and without spasms. PloS one, 13(3), e0193599. https://doi.org/10.1371/journal.pone.0193599.
- Grinspan, Z. M., Shellhaas, R. A., Coryell, J., Sullivan, J. E., Wirrell, E. C., Mytinger, J. R., Gaillard, W. , Kossoff, E. H., Valencia, I., Knupp, K. G., Wusthoff, C., Keator, C., Ryan, N., Loddenkemper, T., Chu, C. J., Novotny, E. J., Jr, Millichap, J., & Berg, A. T. (2018). Comparative Effectiveness of Levetiracetam vs Phenobarbital for Infantile Epilepsy. JAMA pediatrics, 172(4), 352–360. https://doi.org/10.1001/jamapediatrics.2017.5211.
- Perry M. S. (2018). Take Two Deep Breaths and Call Me in the Morning. Epilepsy currents, 18(4), 222–223. https://doi.org/10.5698/1535-7597.18.4.222.
- Perry, M. S., & Poduri, A. (2018). Two Studies, One Message: High Yield of Genetic Testing in Infants and Young Children With Severe Epilepsies. Epilepsy currents, 18(1), 24–26. https://doi.org/10.5698/1535-7597.18.1.24.
We're here to help.
If your child has been diagnosed, you probably have lots of questions. We can help. If you would like to schedule an appointment, refer a patient or speak to our staff, please call our offices at 682-303-2650.