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<div class="score-accordion section-menu-wrapper"> <div class="score-accordion-panel"> <div class="panel-heading"> <div class="panel-title"> <button type="button" class="accordion-button" data-target="#sectionMenu" aria-expanded="false" aria-controls="accordion1"> In This Section </button> </div> </div><div id="sectionMenu" class="panel-collapse collapse"> <div class="panel-body"> <div class="bg-lightgrey"> <ul class="main"> <li class=""> <a href="/es/services/neurosciences-research/" aria-label="Neurosciences Research Center" class="GTMMENU" target="_self"> Neurosciences Research Center </a> </li> </ul> <ul class="level-1"> <li class=""> <a href="/es/services/neurosciences-research/team/" aria-label="Research Team" class="GTMMENU" target="_self"> Research Team </a> </li> <li class=""> <a href="/es/services/neurosciences-research/projects/" aria-label="Research Projects" class="GTMMENU" target="_self"> Research Projects </a> <ul class="level-2"> <li class=""> <a href="/es/services/neurosciences-research/projects/published-research/" class="GTMMENU" target="_self"> Published Research </a> </li> <li class="active"> <a href="/es/services/neurosciences-research/projects/clinical-trials/" class="GTMMENU" target="_self"> Neuroscience Clinical Trials </a> </li> <li class=""> <a href="/es/services/neurosciences-research/projects/nicu/" class="GTMMENU" target="_self"> Neonatal Research </a> </li> <li class=""> <a href="/es/services/neurosciences-research/projects/movement-disorders/" class="GTMMENU" target="_self"> Movement Disorders Research </a> </li> <li class=""> <a href="/es/services/neurosciences-research/projects/cognition/" class="GTMMENU" target="_self"> Cognition, Neuroscience and Mental Health </a> </li> <li class=""> <a href="/es/services/neurosciences-research/projects/epilepsy/american-epilepsy-society-aes-2021-virtual-poster/" aria-label="2021 AES Poster Presentations" class="GTMMENU" target="_self"> 2021 AES Poster Presentations </a> </li> </ul> </li> <li class=""> <a href="/es/services/neurosciences-research/technology/" aria-label="Advanced Technology" class="GTMMENU" target="_self"> Advanced Technology </a> </li> <li class=""> <a href="/es/services/neurosciences-research/funding/" aria-label="Research Grants" class="GTMMENU" target="_self"> Research Grants </a> </li> <li class=""> <a href="/es/services/neurosciences-research/clinical-recruitment/" aria-label="Get involved" class="GTMMENU" target="_self"> Get Involved </a> </li> <li class=""> <a href="https://cookchildrenscareers.hctsportals.com/jobs/search?" aria-label="Research Jobs" class="GTMMENU" target="_self"> Research Jobs </a> </li> </ul> </div> </div> </div> </div> </div> <div class="top-content"> <div class="rte-content"> <p><img src="/siteassets/images/specialties/neurology/banner-clinical-research-main.jpg" alt="banner-clinical-research-main.jpg" width="1920" height="720" /></p> <p>When most people think of medical research they assume that the most advanced research comes from academic affiliations. But here at Cook Children's, we challenge that assumption. Our medical team is deeply involved in research of all kinds. We look for better ways to diagnose, treat and prevent neurological conditions ... and we look for ways to cure them.</p> <p>Cook Children's is at the forefront of leading-edge clinical research and our specialists are actively participating in studies investigating a variety of conditions including epilepsy, stroke and neuromuscular disorders.</p> </div> <div class="trial-block"> <div class="rich-text"><h3>Active trials</h3></div> <ul class="table-to-list"> <li> <div> <p class="title"> <b> A double-blind, randomized, placebo-controlled trial of adjunctive ganaxolone treatment in children and young adults with cyclin-dependent kinase-like 5 (CDKL5) deficiency disorder (CDD) followed by long-term open-label treatment. </b> </p> <p class="investigator"> Investigador primario: <a href="/doctors/neurosciences/dr-m-scott-perry"> <em> M. Scott Perry </em> </a> </p> <p class="case-id"> IRB ID: 2018-090 <span class="text-secondaryblue"> (OPEN) </span> </p> </div> <div> <p> <a href="https://www.clinicaltrials.gov/ct2/show/NCT03572933" class="score-button primary GTMBUTTON" aria-label="Información del estudio"> Información del estudio </a> <br /> <a href="mailto:ResearchHelpDesk@cookchildrens.org?subject=Cook Children's Research Information Request (2018-090)" class="score-button task GTMBUTTON" aria-label="Información requerida"> Información requerida </a> </p> </div> </li> <li> <div> <p class="title"> <b> A Learning Healthcare System for Pediatric Epilepsy </b> </p> <p class="investigator"> Investigador primario: <a href="/doctors/neurosciences/dr-m-scott-perry"> <em> M. Scott Perry </em> </a> </p> <p class="case-id"> IRB ID: 2019-064 <span class="text-secondaryblue"> (OPEN) </span> </p> </div> <div> <p> <a href="mailto:ResearchHelpDesk@cookchildrens.org?subject=Cook Children's Research Information Request (2019-064)" class="score-button task GTMBUTTON" aria-label="Información requerida"> Información requerida </a> </p> </div> </li> <li> <div> <p class="title"> <b> A Long-term Observational Study Evaluating Eteplirsen in Patients with Duchenne Muscular Dystrophy under Conditions of Routine Clinical Practice </b> </p> <p class="investigator"> Investigador primario: <a href="/doctors/neurosciences/dr-warren-a-marks"> <em> Warren A. Marks </em> </a> </p> <p class="case-id"> IRB ID: 2019-007 <span class="text-secondaryblue"> (OPEN) </span> </p> </div> <div> <p> <a href="mailto:ResearchHelpDesk@cookchildrens.org?subject=Cook Children's Research Information Request (2019-007)" class="score-button task GTMBUTTON" aria-label="Información requerida"> Información requerida </a> </p> </div> </li> <li> <div> <p class="title"> <b> A Phase 2, Prospective, Interventional, Open-Label, Multi-Site, Extension Study to Assess the Long-Term Safety and Tolerability of TAK-935 as Adjunctive Therapy in Patients with RareEpilepsy </b> </p> <p class="investigator"> Investigador primario: <a href="/doctors/neurosciences/dr-m-scott-perry"> <em> M. Scott Perry </em> </a> </p> <p class="case-id"> IRB ID: 2019-029 <span class="text-secondaryblue"> (OPEN) </span> </p> </div> <div> <p> <a href="https://www.clinicaltrials.gov/ct2/show/NCT03635073" class="score-button primary GTMBUTTON" aria-label="Información del estudio"> Información del estudio </a> <br /> <a href="mailto:ResearchHelpDesk@cookchildrens.org?subject=Cook Children's Research Information Request (2019-029)" class="score-button task GTMBUTTON" aria-label="Información requerida"> Información requerida </a> </p> </div> </li> <li> <div> <p class="title"> <b> A Prospective, Long Term Registry of Patients with a Diagnosis of Spinal Muscular Atrophy </b> </p> <p class="investigator"> Investigador primario: <a href="/doctors/neurosciences/dr-warren-a-marks"> <em> Warren A. Marks </em> </a> </p> <p class="case-id"> IRB ID: 2019-052 <span class="text-secondaryblue"> (OPEN) </span> </p> </div> <div> <p> <a href="https://www.clinicaltrials.gov/ct2/show/NCT04174157" class="score-button primary GTMBUTTON" aria-label="Información del estudio"> Información del estudio </a> <br /> <a href="mailto:ResearchHelpDesk@cookchildrens.org?subject=Cook Children's Research Information Request (2019-052)" class="score-button task GTMBUTTON" aria-label="Información requerida"> Información requerida </a> </p> </div> </li> <li> <div> <p class="title"> <b> Activa� Dystonia Therapy </b> </p> <p class="investigator"> Investigador primario: <a href="/doctors/neurosciences/dr-warren-a-marks"> <em> Warren A. Marks </em> </a> </p> <p class="case-id"> IRB ID: 593 <span class="text-secondaryblue"> (OPEN) </span> </p> </div> <div> <p> <a href="https://www.clinicaltrials.gov/ct2/show/NCT00580658" class="score-button primary GTMBUTTON" aria-label="Información del estudio"> Información del estudio </a> <br /> <a href="mailto:ResearchHelpDesk@cookchildrens.org?subject=Cook Children's Research Information Request (593)" class="score-button task GTMBUTTON" aria-label="Información requerida"> Información requerida </a> </p> </div> </li> <li> <div> <p class="title"> <b> An Expanded Access Protocol for Use of Triheptanoin in Patients with Glucose Transporter Type-1 Deficiency Syndrome (Glut1 DS) </b> </p> <p class="investigator"> Investigador primario: <a href="/doctors/neurosciences/dr-adrian-lacy"> <em> Adrian Lacy </em> </a> </p> <p class="case-id"> IRB ID: 2019-027 <span class="text-secondaryblue"> (OPEN) </span> </p> </div> <div> <p> <a href="mailto:ResearchHelpDesk@cookchildrens.org?subject=Cook Children's Research Information Request (2019-027)" class="score-button task GTMBUTTON" aria-label="Información requerida"> Información requerida </a> </p> </div> </li> <li> <div> <p class="title"> <b> An Observational Study to Investigate Cognition and Quality of Life in Children and Adolescents with Dravet Syndrome </b> </p> <p class="investigator"> Investigador primario: <a href="/doctors/neurosciences/dr-m-scott-perry"> <em> M. Scott Perry </em> </a> </p> <p class="case-id"> IRB ID: 2019-032 <span class="text-secondaryblue"> (OPEN) </span> </p> </div> <div> <p> <a href="mailto:ResearchHelpDesk@cookchildrens.org?subject=Cook Children's Research Information Request (2019-032)" class="score-button task GTMBUTTON" aria-label="Información requerida"> Información requerida </a> </p> </div> </li> <li> <div> <p class="title"> <b> An Open-Label Extension Study Of Edasalonexent in Pediatric Patients with Duchenne Muscular Dystrophy </b> </p> <p class="investigator"> Investigador primario: <a href="/doctors/neurosciences/dr-warren-a-marks"> <em> Warren A. Marks </em> </a> </p> <p class="case-id"> IRB ID: 2019-084 <span class="text-secondaryblue"> (OPEN) </span> </p> </div> <div> <p> <a href="https://www.clinicaltrials.gov/ct2/show/NCT03917719" class="score-button primary GTMBUTTON" aria-label="Información del estudio"> Información del estudio </a> <br /> <a href="mailto:ResearchHelpDesk@cookchildrens.org?subject=Cook Children's Research Information Request (2019-084)" class="score-button task GTMBUTTON" aria-label="Información requerida"> Información requerida </a> </p> </div> </li> <li> <div> <p class="title"> <b> Cognitive and Neuroimaging Biosignatures of Well-being in Youth with and without Seizures </b> </p> <p class="investigator"> Investigador primario: <a href=""> <em> Crystal Cooper </em> </a> </p> <p class="case-id"> IRB ID: 2020-104 <span class="text-secondaryblue"> (OPEN) </span> </p> </div> <div> <p> <a href="mailto:ResearchHelpDesk@cookchildrens.org?subject=Cook Children's Research Information Request (2020-104)" class="score-button task GTMBUTTON" aria-label="Información requerida"> Información requerida </a> </p> </div> </li> <li> <div> <p class="title"> <b> Comprehensive Epilepsy Center Surgical Database Project </b> </p> <p class="investigator"> Investigador primario: <a href="/doctors/neurosciences/dr-m-scott-perry"> <em> M. Scott Perry </em> </a> </p> <p class="case-id"> IRB ID: 2010-068 <span class="text-secondaryblue"> (OPEN) </span> </p> </div> <div> <p> <a href="mailto:ResearchHelpDesk@cookchildrens.org?subject=Cook Children's Research Information Request (2010-068)" class="score-button task GTMBUTTON" aria-label="Información requerida"> Información requerida </a> </p> </div> </li> <li> <div> <p class="title"> <b> Ictal and Interictal High-Frequency Electrophysiological Activity for the Localization of the Epileptogenic Zone in Children with Refractory Epilepsy </b> </p> <p class="investigator"> Investigador primario: <a href=""> <em> Christos Papadelis PhD </em> </a> </p> <p class="case-id"> IRB ID: 2019-070 <span class="text-secondaryblue"> (OPEN) </span> </p> </div> <div> <p> <a href="mailto:ResearchHelpDesk@cookchildrens.org?subject=Cook Children's Research Information Request (2019-070)" class="score-button task GTMBUTTON" aria-label="Información requerida"> Información requerida </a> </p> </div> </li> <li> <div> <p class="title"> <b> MOVR Data Hub </b> </p> <p class="investigator"> Investigador primario: <a href="/doctors/neurosciences/dr-warren-a-marks"> <em> Warren A. Marks </em> </a> </p> <p class="case-id"> IRB ID: 2019-055 <span class="text-secondaryblue"> (OPEN) </span> </p> </div> <div> <p> <a href="https://www.clinicaltrials.gov/ct2/show/N/A" class="score-button primary GTMBUTTON" aria-label="Información del estudio"> Información del estudio </a> <br /> <a href="mailto:ResearchHelpDesk@cookchildrens.org?subject=Cook Children's Research Information Request (2019-055)" class="score-button task GTMBUTTON" aria-label="Información requerida"> Información requerida </a> </p> </div> </li> <li> <div> <p class="title"> <b> Multi Center iMRI Neurosurgery Database </b> </p> <p class="investigator"> Investigador primario: <a href="/doctors/neurosurgery/dr-john-honeycutt"> <em> John Honeycutt </em> </a> </p> <p class="case-id"> IRB ID: 2013-025 <span class="text-secondaryblue"> (OPEN) </span> </p> </div> <div> <p> <a href="mailto:ResearchHelpDesk@cookchildrens.org?subject=Cook Children's Research Information Request (2013-025)" class="score-button task GTMBUTTON" aria-label="Información requerida"> Información requerida </a> </p> </div> </li> <li> <div> <p class="title"> <b> Multi-modal neuroimaging in children with cerebral palsy to assess functional and anatomical reorganization in relation to sensory and motor functions </b> </p> <p class="investigator"> Investigador primario: <a href=""> <em> Christos Papadelis PhD </em> </a> </p> <p class="case-id"> IRB ID: 2019-068 <span class="text-secondaryblue"> (OPEN) </span> </p> </div> <div> <p> <a href="mailto:ResearchHelpDesk@cookchildrens.org?subject=Cook Children's Research Information Request (2019-068)" class="score-button task GTMBUTTON" aria-label="Información requerida"> Información requerida </a> </p> </div> </li> <li> <div> <p class="title"> <b> Observational study in infants and children with SCN1A+ Dravet Syndrome </b> </p> <p class="investigator"> Investigador primario: <a href="/doctors/neurosciences/dr-m-scott-perry"> <em> M. Scott Perry </em> </a> </p> <p class="case-id"> IRB ID: 2020-056 <span class="text-secondaryblue"> (OPEN) </span> </p> </div> <div> <p> <a href="mailto:ResearchHelpDesk@cookchildrens.org?subject=Cook Children's Research Information Request (2020-056)" class="score-button task GTMBUTTON" aria-label="Información requerida"> Información requerida </a> </p> </div> </li> <li> <div> <p class="title"> <b> Parental Attitudes in Neonatal Clinical Trial Enrollment:Decision-Making Preferences and Reasoning among Participants and Non-Participants </b> </p> <p class="investigator"> Investigador primario: <a href="/doctors/neonatology/dr-david-riley"> <em> David Riley </em> </a> </p> <p class="case-id"> IRB ID: 2017-016 <span class="text-secondaryblue"> (OPEN) </span> </p> </div> <div> <p> <a href="mailto:ResearchHelpDesk@cookchildrens.org?subject=Cook Children's Research Information Request (2017-016)" class="score-button task GTMBUTTON" aria-label="Información requerida"> Información requerida </a> </p> </div> </li> <li> <div> <p class="title"> <b> Pediatric International DBS (PEDiDBS) Registry </b> </p> <p class="investigator"> Investigador primario: <a href="/doctors/neurosciences/dr-warren-a-marks"> <em> Warren A. Marks </em> </a> </p> <p class="case-id"> IRB ID: 2016-013 <span class="text-secondaryblue"> (OPEN) </span> </p> </div> <div> <p> <a href="mailto:ResearchHelpDesk@cookchildrens.org?subject=Cook Children's Research Information Request (2016-013)" class="score-button task GTMBUTTON" aria-label="Información requerida"> Información requerida </a> </p> </div> </li> <li> <div> <p class="title"> <b> Phase I Dravet Syndrome study in Children and Adolescents </b> </p> <p class="investigator"> Investigador primario: <a href="/doctors/neurosciences/dr-m-scott-perry"> <em> M. Scott Perry </em> </a> </p> <p class="case-id"> IRB ID: 2020-012 <span class="text-secondaryblue"> (OPEN) </span> </p> </div> <div> <p> <a href="mailto:ResearchHelpDesk@cookchildrens.org?subject=Cook Children's Research Information Request (2020-012)" class="score-button task GTMBUTTON" aria-label="Información requerida"> Información requerida </a> </p> </div> </li> <li> <div> <p class="title"> <b> Quantitative Assessment of Sucking for Early Diagnosis of Brain Injury in Infants at High Risk </b> </p> <p class="investigator"> Investigador primario: <a href=""> <em> Christos Papadelis PhD </em> </a> </p> <p class="case-id"> IRB ID: 2019-085 <span class="text-secondaryblue"> (OPEN) </span> </p> </div> <div> <p> <a href="mailto:ResearchHelpDesk@cookchildrens.org?subject=Cook Children's Research Information Request (2019-085)" class="score-button task GTMBUTTON" aria-label="Información requerida"> Información requerida </a> </p> </div> </li> <li> <div> <p class="title"> <b> The �HEAL� Study, High-Dose Erythropoietin for Asphyxia and Encephalopathy (A randomized, placebo-controlled, double-masked 500-subject clinical trial of erythropoietin for the treatment of neonatal hypoxic-ischemic encephalopathy) </b> </p> <p class="investigator"> Investigador primario: <a href="/doctors/neonatology/dr-david-riley"> <em> David Riley </em> </a> </p> <p class="case-id"> IRB ID: 2017-010 <span class="text-secondaryblue"> (OPEN) </span> </p> </div> <div> <p> <a href="https://www.clinicaltrials.gov/ct2/show/NCT02811263" class="score-button primary GTMBUTTON" aria-label="Información del estudio"> Información del estudio </a> <br /> <a href="mailto:ResearchHelpDesk@cookchildrens.org?subject=Cook Children's Research Information Request (2017-010)" class="score-button task GTMBUTTON" aria-label="Información requerida"> Información requerida </a> </p> </div> </li> </ul> </div> <div class=""> <div class="rich-text"><h2 style="margin-top: -60px;">We're here to help.</h2> <p>If your child has been diagnosed, you probably have lots of questions. 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